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Description

To maintain redox homeostasis, neurons rely on antioxidant systems such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) to neutralize free radicals

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The evidence that hypotaurine, through its binding to soluble A, reduces the production and aggregation of oligomers, as well as its ability to lessen the toxicity of -amyloid (A) in primary cultured neurons and amyloid plaques in a mouse model, provides support for this assertion (129)

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